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Raw cornstarch as an additional therapy in nesidioblastosis
A Boneh1, H Landau, N Abramovitch
1Department of Paediatrics and Clinical Nutrition, Hadassah Medical Centre, Jerusalem, Israel.
The American Journal of Clinical Nutrition
|June 1, 1988
Summary
Raw cornstarch effectively managed blood glucose levels in children with nesidioblastosis, preventing hypoglycemia after surgery. This dietary intervention supported normal development and growth in the study participants.
Area of Science:
- Pediatric Endocrinology
- Metabolic Disorders
Background:
- Nesidioblastosis is a rare condition causing persistent hypoglycemia.
- Subtotal distal pancreatectomy is a surgical option, but often requires intensive management.
- Post-surgical hypoglycemia necessitates continuous feeding strategies.
Observation:
- Two children with nesidioblastosis experienced symptomatic hypoglycemia despite frequent feedings and continuous nocturnal intragastric polycose.
- Conventional management strategies were insufficient to maintain normoglycemia.
Findings:
- Oral administration of raw cornstarch consistently normalized blood glucose levels in both children.
- No further hypoglycemic episodes were reported after initiating raw cornstarch treatment.
- Children maintained normal development and satisfactory growth during 22 months of follow-up.
Implications:
- Raw cornstarch represents a viable, effective therapeutic option for managing hypoglycemia in nesidioblastosis.
- This approach may reduce the need for intensive continuous feeding regimens.
- Further research into the use of complex carbohydrates for glycemic control in pediatric endocrine disorders is warranted.