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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

167
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Related Experiment Video

Updated: Dec 10, 2025

Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer
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Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

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Using Low-Dose Computed Tomography for Early Detection of Lung Cancer.

Kristi S Rulli, Eric Matthews

    Radiologic Technology
    |September 4, 2020
    PubMed
    Summary

    Low-dose computed tomography (LD-CT) detects lung cancer earlier in high-risk Kentucky populations at a higher rate than previously reported. This early detection using LD-CT can improve patient outcomes and reduce healthcare costs.

    Keywords:
    early cancer detection toolslow-dose computed tomographylung cancerlung cancer detectionlung cancer incidencelung cancer mortality

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    Author Spotlight: Advancing 3D Modeling for Enhanced Diagnosis and Treatment of Pulmonary Nodules in Early-Stage Lung Cancer
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    Author Spotlight: Advancing 3D Modeling for Enhanced Diagnosis and Treatment of Pulmonary Nodules in Early-Stage Lung Cancer

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    Author Spotlight: Advancing 3D Modeling for Enhanced Diagnosis and Treatment of Pulmonary Nodules in Early-Stage Lung Cancer
    07:53

    Author Spotlight: Advancing 3D Modeling for Enhanced Diagnosis and Treatment of Pulmonary Nodules in Early-Stage Lung Cancer

    Published on: October 13, 2023

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    Area of Science:

    • Pulmonology
    • Oncology
    • Radiology

    Background:

    • Lung cancer remains a significant public health concern, particularly in high-risk populations.
    • Early detection is crucial for improving patient survival rates and treatment efficacy.
    • Low-dose computed tomography (LD-CT) is a key screening tool for identifying lung cancer in its early stages.

    Purpose of the Study:

    • To evaluate the rate of early lung cancer detection using LD-CT in a high-risk Kentucky population.
    • To compare these detection rates with those from the National Lung Screening Trial (NLST).
    • To assess if LD-CT influences cancer staging and if NLST findings are reproducible.

    Main Methods:

    • Retrospective review of medical records from 2924 high-risk patients (aged 55-79) who underwent LD-CT between 2015-2017.
    • Inclusion criteria: significant smoking history (≥30 pack-years or quit within 15 years).
    • Exclusion criteria: prior cancer diagnosis.

    Main Results:

    • An average of 2 lung cancer diagnoses per 100 LD-CT scans were identified, significantly higher than the NLST's rate of 1 per 320 scans.
    • Sixty-six patients (2.26%) were diagnosed with lung cancer.
    • The mortality rate associated with lung cancer in this cohort was 239 per 100,000 patients.

    Conclusions:

    • Lung cancer is diagnosed at a higher rate in Kentucky residents compared to NLST findings, indicating a greater risk in this population.
    • LD-CT is effective for early lung cancer detection in asymptomatic, high-risk individuals.
    • Implementing LD-CT screening can potentially improve quality of life, prolong survival, and reduce healthcare expenditures.