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Updated: Dec 10, 2025

A Modified Precipitation Method to Isolate Urinary Exosomes
Published on: January 16, 2015
Advances in study on exosomes and their applications in kidney diseases
Can Chen1,2, Meichu Cheng3
1Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha 410011. 2576796992@qq.com.
Abstract:
Exosomes are in a size of 30-100 nm vesicles released by various cells, with a double-layered lipid membrane containing DNA, RNA, and protein. In the past, exosomes were considered to be molecular waste, and recently exosomes have been shown to be involved in many pathophysiological processes, including intercellular communication, immune response, nerve repair, and tumorigenesis. Exosomes are present in numerous body fluids, and urinary exosomes have been shown to be biomarkers of a variety of kidney diseases.
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