Related Experiment Videos
Agnathia, holoprosencephaly, and situs inversus: report of a case
R W Leech1, L S Bowlby, R A Brumback
1Department of Pathology, University of Oklahoma College of Medicine, Oklahoma City 73190.
American Journal of Medical Genetics
|March 1, 1988
Abstract:
We present the first documented case of agnathia-holoprosencephaly (an uncommon form of craniofacial anomaly) associated with situs inversus. This case may represent the concordance of multiple field complex anomalies, but the possibility of a major midline malformation (situs inversus) caused by a timed insult (environmental or genetic) which affects multiple structures and occurs concurrently with a major field defect during early embryogenesis cannot be excluded.