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Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
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The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
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Sub-cycle atomic-scale forces coherently control a single-molecule switch.

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Researchers used terahertz waves to apply ultrafast forces, controlling atomic motion in molecules. This breakthrough enables precise manipulation for chemical reactions and phase transitions at the atomic scale.

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Area of Science:

  • Physics
  • Chemistry
  • Materials Science

Background:

  • Scanning probe techniques utilize precise forces for atomic manipulation.
  • Exploiting ultrafast dynamics for coherent atomic-scale control is a significant challenge.

Purpose of the Study:

  • To demonstrate femtosecond atomic-scale force application for selective molecular motion.
  • To achieve coherent control over molecular dynamics using lightwave-driven forces.

Main Methods:

  • Utilized lightwave-driven scanning tunneling microscopy.
  • Employed ultrafast action spectroscopy with terahertz waves confined to an atomically sharp tip.

Main Results:

  • Achieved selective, coherent hindered rotation in magnesium phthalocyanine molecules.
  • Modulated molecular switching probability by up to 39% using femtosecond forces.
  • Demonstrated atomic-scale force application within less than an optical cycle.

Conclusions:

  • Developed a method for coherent manipulation of atomic motion using ultrafast forces.
  • Opens possibilities for controlling chemical reactions and phase transitions at intrinsic scales.