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Updated: Dec 10, 2025
04:23
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
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Transfusion-transmissible dengue infections
Lakshika Perera1,2, Nandrani De Zoysa2, Umesh Jayarajah1,2
1Department of Surgery, Faculty of Medicine, University of Colombo, Colombo 8, Sri Lanka.
Transactions of the Royal Society of Tropical Medicine and Hygiene
|September 4, 2020
Summary
Dengue virus (DENV) can spread through blood transfusions from asymptomatic donors. Reliable screening tests are crucial in endemic regions to prevent transfusion-transmitted dengue and ensure blood safety.
Area of Science:
- Medical Entomology
- Infectious Diseases
- Public Health
Background:
- Dengue is a significant global health concern, prevalent in numerous countries.
- Limited data exists regarding dengue transmission via blood transfusions.
Purpose of the Study:
- To review and summarize existing literature on transfusion-transmitted dengue.
- To highlight the risk of dengue virus transmission through blood donation.
Main Methods:
- A comprehensive literature search was performed.
- Databases used included PubMed, Scopus, Embase, and Google Scholar.
Main Results:
- Apparently healthy blood donors can be infected with dengue virus (DENV).
- These infected donors pose a risk of transmitting DENV to transfusion recipients.
Conclusions:
- Identifying and excluding infected donors at the screening stage is challenging.
- Implementing reliable screening tests in high-endemic areas is essential for blood supply safety.
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