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Peripheral exudative haemorrhagic chorioretinopathy: a widefield imaging study
Federico Zicarelli1, Chiara Preziosa2, Giovanni Staurenghi2
1University of Milan Department of Biomedical and Clinical Sciences Luigi Sacco, Milan, Italy federicozicarelli@gmail.com.
The British Journal of Ophthalmology
|September 5, 2020
Summary
Peripheral exudative haemorrhagic chorioretinopathy (PEHCR) involves peripheral subretinal fluid and neovascular networks. Peripheral exudation and lesion extension are risk factors for macular involvement, warranting active treatment in high-risk eyes.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Medical Imaging
Background:
- Peripheral exudative haemorrhagic chorioretinopathy (PEHCR) is a condition affecting the peripheral retina.
- Understanding its imaging features and progression is crucial for patient outcomes.
Purpose of the Study:
- To analyze widefield imaging findings in PEHCR.
- To identify risk factors for disease progression, specifically macular involvement (MI) and intravitreal bleeding (IVB).
- To compare different treatment modalities for PEHCR.
Main Methods:
- Retrospective analysis of clinical and imaging data from 50 eyes of 35 patients.
- Utilized widefield imaging, including near-infrared reflectance, fluorescein angiography, indocyanine green angiography, and optical coherence tomography.
- Classified lesions based on treatment and prognostic index for MI and IVB.
Main Results:
- Widefield imaging revealed peripheral subretinal fluid (SRF) in 62% and peripheral neovascular networks in 84% of eyes.
- MI occurred in 34% and IVB in 14% of eyes, correlating with SRF and lesion grade.
- Anti-VEGF and combined anti-VEGF/PDT treatments inversely correlated with MI incidence in eyes with risk factors.
Conclusions:
- Peripheral subretinal exudation and extent of peripheral involvement are risk factors for MI in PEHCR.
- Active treatment is recommended for high-risk eyes with PEHCR to mitigate progression.
