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Unusual Brain MRI Pattern in 2 Patients with COVID-19 Acute Respiratory Distress Syndrome
S Toledano-Massiah1, N Badat2, A Leberre2
1From the Department of Radiology (S.T.-M., N.B., A.L., S.G., M.Z., J.H.) stoledano@hpsj.fr.
AJNR. American Journal of Neuroradiology
|September 5, 2020
Summary
Two patients with coronavirus disease 2019 showed unique brain MRI findings. Unusual diffusion-weighted imaging patterns with white matter lesions suggest potential neurological complications of COVID-19.
Area of Science:
- Neurology
- Radiology
- Infectious Diseases
Background:
- Coronavirus disease 2019 (COVID-19) is a global pandemic with diverse clinical manifestations.
- Neurological complications of COVID-19 are increasingly reported, necessitating further investigation into their underlying mechanisms.
Observation:
- Two intensive care unit patients with confirmed COVID-19 infection underwent brain Magnetic Resonance (MR) imaging.
- The MR imaging revealed an unusual diffusion-weighted imaging (DWI) pattern.
Findings:
- The DWI pattern demonstrated characteristic nodular and ring-shaped lesions.
- These lesions were observed in the periventricular and deep white matter regions of the brain.
Implications:
- These findings suggest a potential link between COVID-19 infection and specific white matter abnormalities.
- Further research is warranted to elucidate the pathogenesis of these neurological manifestations and their clinical significance.
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