Perforated Goblet Cell Carcinoid of the Appendix.

Area of Science:

• Gastroenterology
• Oncology
• Pathology

Background:

• Goblet cell carcinoid (GCC) of the appendix is an uncommon neuroendocrine tumor.
• Its clinical presentation, pathological characteristics, and prognosis are not well-established.
• Appendiceal neoplasms can present with acute appendicitis symptoms.

Observation:

• A 71-year-old female presented with symptoms of acute appendicitis, including abdominal pain, vomiting, and fever.
• Intraoperative findings revealed an enlarged and perforated appendix.
• Histopathological examination confirmed Goblet cell carcinoid (GCC) with subserosal invasion.

Findings:

• The patient underwent successful laparoscopic ileocecal resection with D3 lymph node dissection.
• Post-operative histopathology confirmed no residual tumor or lymph node metastasis.
• This case represents a rare instance of appendiceal GCC presenting as a perforated appendix.

Implications:

• This case contributes valuable data to the limited literature on appendiceal GCC.
• It underscores the importance of considering rare appendiceal neoplasms in the differential diagnosis of acute appendicitis.
• Accurate pathological diagnosis is crucial for appropriate surgical management and prognosis of appendiceal GCC.