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Craniofacial Collaboration UK: Developmental Outcomes in 5-Year-Old Children With Sagittal Synostosis

Helen Care1, Patrick Kennedy-Williams1, Laura Culshaw2

  • 1Oxford Craniofacial Unit, Oxford University Hospitals NHS Foundation Trust.

The Journal of Craniofacial Surgery
|September 5, 2020
PubMed

Insights

Children with single-suture sagittal synostosis (SS) generally develop typically by age 5. However, they show increased fine motor and hyperactivity issues, alongside unexpectedly strong problem-solving skills.

Area of Science:

  • Pediatric developmental outcomes
  • Craniosynostosis research
  • Clinical child psychology

Background:

  • Single-suture sagittal synostosis (SS) is a common craniosynostosis affecting skull development.
  • Previous research on developmental outcomes in SS patients has limitations due to data heterogeneity.
  • The Craniofacial Collaboration UK (CC-UK) initiative aims to collect robust, standardized data.

Purpose of the Study:

  • To outline developmental outcomes at age 5 for children with SS post-primary surgery.
  • To compare developmental trajectories of SS children with normative data.
  • To identify potential early indicators of subtle neurodevelopmental differences.

Main Methods:

  • Systematically collected, robust data from clinically and chronologically homogenous samples.
  • Assessment of developmental, behavioral, and emotional domains at age 5.
  • Comparison of SS cohort group means against established normative data.

Main Results:

  • Majority of children with SS perform within the average range across developmental domains.
  • Significantly greater difficulties observed in fine motor skills and hyperactivity compared to peers.
  • Unexpectedly superior problem-solving skills noted in the SS cohort.

Conclusions:

  • Most children with SS demonstrate broadly typical development by age 5.
  • Subtle but significant differences in fine motor skills, hyperactivity, and problem-solving warrant further investigation.
  • Longitudinal follow-up is crucial for understanding developmental trajectories and identifying at-risk subgroups.

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