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Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
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Updated: Dec 9, 2025

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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New Directions in Ensuring Catheter Safety.

Khaled Boubes1, Aisha Shaikh2, Zygimantas Alsauskas3

  • 1The Ohio State University, Columbus, OH.

Advances in Chronic Kidney Disease
|September 6, 2020
PubMed
Summary

Tunneled dialysis catheters are common for hemodialysis but linked to poor outcomes. Innovation is needed to improve dialysis vascular access and reduce patient morbidity and mortality.

Keywords:
Catheter safetyDialysis vascular accessHemodialysisTunneled dialysis catheters

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Area of Science:

  • Nephrology
  • Vascular Surgery
  • Biomedical Engineering

Background:

  • Tunneled dialysis catheters are the primary method for initiating hemodialysis.
  • Their use is associated with significant morbidity and mortality compared to arteriovenous fistulae or grafts.

Purpose of the Study:

  • To review the current state of tunneled dialysis catheters.
  • To highlight the need for innovation in dialysis vascular access.

Main Methods:

  • Review of existing literature on tunneled dialysis catheters.
  • Analysis of catheter designs, materials, and associated complications.

Main Results:

  • Different catheter types exhibit varying functional properties.
  • Adjunctive devices and medications can mitigate infection and thrombosis rates.

Conclusions:

  • Current tunneled dialysis catheters do not meet optimal performance goals.
  • Significant innovation is required in the field of dialysis vascular access.