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Goblet cell carcinoids of the appendix.
R S Berardi1, S S Lee, H P Chen
1Department of Surgery, Veterans Administration Medical Center, Des Moines, Iowa 50310.
Surgery, Gynecology & Obstetrics
|July 1, 1988
Summary
Goblet cell carcinoid of the appendix is a distinct tumor with features between carcinoid and adenocarcinoma. Simple appendectomy offers a generally good prognosis for this appendiceal neoplasm.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Goblet cell carcinoid (GCC) of the appendix presents unique diagnostic challenges.
- Its biologic behavior is considered intermediate between appendiceal carcinoid tumors and well-differentiated adenocarcinoma.
- The histogenesis of GCC remains a subject of ongoing research and debate.
Purpose of the Study:
- To review the characteristics of goblet cell carcinoid of the appendix.
- To discuss its diagnostic features and histogenesis.
- To evaluate the prognosis and treatment of this appendiceal tumor.
Main Methods:
- Literature review of goblet cell carcinoid of the appendix.
- Analysis of histological features.
- Evaluation of clinical behavior and treatment outcomes.
Main Results:
- Goblet cell carcinoid of the appendix exhibits distinctive histological features aiding diagnosis.
- The tumor's biologic behavior is intermediate, posing diagnostic considerations.
- Histogenesis is not fully established.
Conclusions:
- Goblet cell carcinoid of the appendix is a distinct entity with specific histological characteristics.
- Simple appendectomy is the recommended treatment for most cases.
- The prognosis for patients treated with appendectomy is generally favorable.