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Effect of Sleep Disorders on Blood Pressure and Hypertension in Children
Lourdes M DelRosso1, Maria Paola Mogavero2, Raffaele Ferri3
1Pediatric Pulmonary and Sleep Medicine, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA, 98105, USA. lourdesdelrosso@me.com.
Insights
Sleep disorders are linked to hypertension in children, with evidence suggesting early cardiovascular changes. Obstructive sleep apnea in children can cause increased sympathetic activity and elevated blood pressure.
Area of Science:
- Pediatric Cardiology
- Sleep Medicine
- Hypertension Research
Background:
- Adult studies clearly link sleep disorders, poor sleep quality, and sleep deprivation to hypertension and cardiovascular risk.
- Evidence in children is less robust but indicates early cardiovascular changes associated with sleep disorders.
- Sleep disorders are increasingly recognized as a significant factor in pediatric health.
Purpose of the Study:
- To review the pathophysiologic basis of hypertension in children with sleep disorders.
- To synthesize current medical literature on the link between sleep disorders and hypertension in pediatric populations.
- To highlight the cardiovascular implications of sleep disturbances in children.
Main Methods:
- Literature review of existing medical studies.
- Analysis of pathophysiologic mechanisms connecting sleep disorders and hypertension.
- Synthesis of evidence from pediatric and adult sleep and hypertension research.
Main Results:
- Children with obstructive sleep apnea exhibit increased sympathetic activation during sleep.
- Evidence suggests blunted blood pressure dipping or elevated pressures in children with obstructive sleep apnea.
- While data on narcolepsy and restless legs syndrome in children is limited, adult data and some pediatric findings exist.
Conclusions:
- Sleep disorders represent a critical, yet often overlooked, factor in pediatric hypertension.
- Early identification and management of sleep disorders may mitigate cardiovascular risk in children.
- Further research is needed to fully elucidate the complex relationship between various sleep disorders and hypertension in children.
Purpose Of Review:
In this review, we aim to discuss the pathophysiologic basis of hypertension in sleep disorders and the current evidence in the medical literature linking sleep disorders and hypertension in children.
Recent Findings:
The medical literature in adults is clear about the contribution of sleep disorders, poor sleep quality, and sleep deprivation to hypertension and increased cardiovascular risk. The literature on cardiovascular consequences of sleep disorders in children is not as robust, but there is some evidence of early cardiovascular changes in children with sleep deprivation and obstructive sleep apnea. Children with obstructive sleep apnea have increased sympathetic activation during sleep, blunted dipping, or elevated systolic or diastolic pressures. Although the literature on other sleep disorders such as narcolepsy and restless legs syndrome is scarce, there is evidence in adults and some recent supportive data in children.
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