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Retinal Vasoproliferative Tumor in Ocular Albinism
Wael A Alsakran1, Nada H Almadhi1, Abdulaziz A Alshamrani1
1Vitreoretinal Division, King Khaled Eye Specialist Hospital (KKESH), Riyadh, Saudi Arabia.
The American Journal of Case Reports
|September 8, 2020
Summary
This study reports the first known case of retinal vasoproliferative tumor (VPT) in a patient with ocular albinism. This finding suggests retinal VPT should be considered in patients with ocular albinism presenting with vision changes.
Area of Science:
- Ophthalmology
- Genetics
- Oncology
Background:
- Retinal vasoproliferative tumor (VPT) is an ocular vascular tumor, often idiopathic but can be linked to secondary conditions.
- Ocular albinism is an X-linked inherited disorder characterized by ocular pigmentary anomalies with minimal skin/hair involvement.
Observation:
- A 42-year-old man with ocular albinism and myopia experienced gradual vision loss.
- Examination revealed nystagmus, iris transillumination defects, depigmented fundus, foveal hypoplasia, and a unilateral retinal vascular lesion.
- Imaging confirmed the lesion's retinal location and vascular nature.
Findings:
- This is the first reported instance of retinal vasoproliferative tumor (VPT) associated with ocular albinism.
- While various treatments exist, observation may suffice if no secondary complications arise.
Implications:
- Retinal VPT should be considered in the differential diagnosis of retinal vascular abnormalities in individuals with ocular albinism.
- This association expands the known spectrum of ocular complications in ocular albinism.
