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Updated: Dec 9, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
A cautionary tale of an emergency cerebrovascular procedure in the COVID-19 era
Hossam Abdou1, Besher Tolaymat2, Felecia Jinwala2
1Department of Surgery, University of Maryland Medical Center, Baltimore, Md.
Insights
A patient experienced anaphylaxis to sugammadex after carotid endarterectomy. Delayed reintubation due to institutional policies highlights risks in critical care during the COVID-19 pandemic.
Area of Science:
- Anesthesiology
- Critical Care Medicine
- Neurology
Background:
- The COVID-19 pandemic significantly impacted healthcare system processes, particularly airway management.
- Stroke patients require urgent surgical intervention, such as carotid endarterectomy, for effective treatment.
Observation:
- A 37-year-old female stroke patient developed anaphylaxis upon extubation following a carotid endarterectomy.
- The anaphylactic reaction was attributed to sugammadex, a neuromuscular reversal agent.
- Institutional policies and resource limitations led to a delay in reintubation.
Findings:
- Despite the delay, the patient experienced no lasting neurological deficits.
- The case underscores the potential for existing healthcare policies to precipitate adverse events in critical care settings.
- Sugammadex-induced anaphylaxis can pose a significant challenge in emergency surgical scenarios.
Implications:
- There is a critical need to review and revise institutional policies to prevent delays in essential procedures like reintubation.
- Healthcare systems must adapt to manage rare but severe complications, such as sugammadex anaphylaxis, especially during public health crises.
- Improving airway management protocols and resource allocation is crucial for patient safety in neurovascular surgery.
Abstract:
The coronavirus disease 2019 pandemic has had an impact on system processes, with airway management being significantly affected. A 37-year-old woman diagnosed with stroke was found to have a filling defect at the origin of the right internal carotid artery. She was taken to the operating room urgently for carotid endarterectomy. The procedure was uneventful; however, anaphylaxis developed on extubation, subsequently attributed to sugammadex. Institutional policies and limited resources resulted in delayed reintubation. Fortunately, she did not have lasting deficits, but this highlights the potential of current policies to lead to complications and the need to improve policies to minimize harm.
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Cardiac Catheterization I: Pre-Procedure Overview
Aneurysm IV: Nursing Management

