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Cognitive Function in Kidney Transplantation
Andrew Jurgensen1, Abd Assalam Qannus1, Aditi Gupta1,2
1Division of Nephrology, Kidney Institute and Center for Transplantation, Kansas City, KS.
Current Transplantation Reports
|September 9, 2020
Summary
Cognitive impairment is prevalent in kidney transplant recipients, impacting their quality of life and transplant outcomes. Early identification and intervention are crucial for better patient management and graft survival.
Area of Science:
- Nephrology
- Neuroscience
- Transplantation Medicine
Background:
- Cognitive impairment is a frequent complication in kidney transplant recipients.
- It significantly impacts quality of life, graft survival, morbidity, and mortality.
- Understanding cognitive function is vital for pre-transplant evaluation and post-transplant care.
Purpose of the Study:
- To review the epidemiology, diagnosis, pathophysiology, and future directions of cognitive impairment in kidney transplantation.
- To explore the influence of pre-transplant cognition, immunosuppression, and peri-transplant factors on post-transplant cognitive function.
Main Methods:
- This is a review article.
- Literature search on cognitive impairment in kidney transplant recipients.
- Synthesis of current knowledge on epidemiology, diagnosis, pathophysiology, and risk factors.
Main Results:
- A majority of kidney transplant patients experience cognitive impairment.
- Cognitive impairment affects both pre-transplant assessments and post-transplant results.
- Undiagnosed cognitive impairment can lead to delayed or inadequate care and interventions.
Conclusions:
- Cognitive impairment is common and significantly affects outcomes in kidney transplant patients.
- Further research is needed to identify modifiable risk factors.
- Interventions to mitigate cognitive decline in kidney disease patients require further investigation.
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