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Updated: Dec 9, 2025

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
Helix self-assembly through the coiling of cylindrical micelles
Sheng Zhong1, Honggang Cui1, Zhiyun Chen2
1Department of Materials Science and Engineering and Delaware Biotechnology Institute, University of Delaware, Newark, DE 19716, USA. pochan@udel.edu.
Abstract:
Both single and double helical superstructures have been created through solution self-assembly of cylindrical micelles for the first time. Helical micelles were formed from the co-assembly of poly(acrylic acid)-block-poly(methyl acrylate)-block-polystyrene (PAA-b-PMA-b-PS) triblock copolymers with different multiamines. The helix pitch could be adjusted by adjusting the amount and type of multiamine added. The helical structure exhibits unprecedented regularity for a nanostructure self-assembled from solution indicating the presence of strong, synergistic forces underlying the helix formation.
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