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Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
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Inflammatory Myofibroblastic Tumour.

Pedro Pimentel Duarte1, Rafaela Sousa1, Mariana Chaves1

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European Journal of Case Reports in Internal Medicine
|September 10, 2020
PubMed
Summary
This summary is machine-generated.

Inflammatory myofibroblastic tumour (IMT) is a rare pancreatic neoplasm. Glucocorticoid therapy effectively treated an unresectable IMT in a young woman, demonstrating a positive response and tumor regression.

Keywords:
Abdominal paininflammatory myofibroblastic tumourneoplasmretroperitoneal space

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Area of Science:

  • Oncology
  • Pathology

Background:

  • Inflammatory myofibroblastic tumour (IMT) is a rare mesenchymal neoplasm.
  • While often benign, IMT can exhibit malignant behavior, including recurrence and metastasis.

Purpose of the Study:

  • To present a case of a young woman with a large pancreatic IMT.
  • To highlight the diagnostic findings and treatment response in this rare pancreatic tumor.

Main Methods:

  • Case report of a young woman presenting with weight loss and abdominal pain.
  • Diagnostic imaging revealed a large pancreatic mass.
  • Histopathological examination confirmed fusocellular mesenchymal neoplasia consistent with IMT.
  • Treatment with glucocorticoids was initiated for unresectable tumor.

Main Results:

  • The pancreatic mass was diagnosed as inflammatory myofibroblastic tumour (IMT).
  • The unresectable tumor showed an excellent response to glucocorticoid therapy.
  • Significant tumor regression was observed following treatment.

Conclusions:

  • Inflammatory myofibroblastic tumour (IMT) is a rare entity with diverse clinical presentations due to its varied locations.
  • While typically benign, IMT carries a risk of relapse and metastasis.
  • Glucocorticoid therapy can be an effective treatment option for unresectable IMT.