Glucosinolates and Isothiocyanates from Moringa oleifera: Chemical and Biological Approaches

Alternative therapies, such as phytotherapy, are considered to improve the health status of people with chronic non-communicable diseases (CNCDs). In this regard, Moringa oleifera is currently being studied for its nutritional value and its total phenolic content. Besides phenolic compounds, the phytochemical composition is also of great interest. This composition is characterized by the presence of glucosinolates and isothiocyanates. Isothiocyanates formed by the biotransformation of Moringa glucosinolates contain an additional sugar in their chemical structure, which provides stability to these bioactive compounds over other isothiocyanates found in other crops. Both glucosinolates and isothiocyanates have been described as beneficial for the prevention and improvement of some chronic diseases. The content of glucosinolates in Moringa tissues can be enhanced by certain harvesting methods which in turn alters their final yield after extraction. This review aims to highlight certain features of glucosinolates and isothiocyanates from M. oleifera, such as their chemical structure, functionality, and main extraction and harvesting methods. Some of their health-promoting effects will also be addressed.