Related Experiment Video
Updated: Dec 9, 2025
08:51
Author Spotlight: Dissection of Adult Mouse Stria Vascularis for Single-Nucleus Sequencing or Immunostaining
Published on: April 21, 2023
4.1K
[Diastematomyelia discovered in adulthood].
F Grailet1, B Maillard2, M Tomasella2
1Faculté de Médecine, ULiège, Belgique.
Revue Medicale De Liege
|September 10, 2020
Summary
This case study highlights diastematomyelia, a rare adult congenital anomaly causing lumbar pain. Early diagnosis and proper management are crucial to prevent neurological deterioration.
Area of Science:
- Neurology
- Medical Imaging
- Congenital Abnormalities
Background:
- Diastematomyelia is a rare congenital spinal malformation, typically diagnosed in utero.
- Adult presentation of diastematomyelia is uncommon and often discovered incidentally.
- Recurrent lumbar pain and cruralgia can be presenting symptoms in adults.
Observation:
- A 35-year-old woman presented with chronic lumbar pain and left-sided leg pain (cruralgia).
- Imaging revealed a congenital anomaly, later diagnosed as diastematomyelia.
- This diagnosis was made fortuitously through a scanner (CT scan).
Findings:
- Diastematomyelia, a split spinal cord malformation, is rare in adulthood.
- Associated malformations can suggest the presence of diastematomyelia.
- The case underscores the importance of thorough iconographic assessment.
Implications:
- Management strategies for adult diastematomyelia remain controversial.
- Inadequate management can result in significant and disabling neurological deficits.
- This case emphasizes the need for increased awareness and diagnostic vigilance for spinal malformations in adults presenting with chronic pain.
Related Concept Videos
01:33Adult Stem Cells
32.5K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
32.5K
01:21Satellite Stem Cells and Muscular Dystrophy
2.2K
Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
2.2K
01:22Mitral Stenosis I: Introduction
211
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
211
01:23Mitral Stenosis II: Clinical features and Diagnostic Tests
120
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
120
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
114
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
114
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
236
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
236