Related Experiment Video
Updated: Dec 9, 2025
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
How useful are cervical Pap smears in detecting endometrial carcinomas? A tertiary cancer center experience
Shailee P Mehta1, Trupti S Patel1, Torsha Jana1
1Department of Oncopathology, Gujarat Cancer And Research Institute, Ahmedabad, Gujarat, India.
Objective:
To determine the role of routine cervical Pap smears in detecting endometrial carcinomas.
Method:
A retrospective study was carried out from the histopathology archives for cases diagnosed as endometrial carcinomas with Pap smears within 6 months before histological diagnosis. The demographic details, reports of Pap smears and other tumor parameters on histopathology were noted.
Results:
We identified 380 of 482 cases of endometrial carcinoma with a documented Pap smear within 6 months before histopathogical diagnosis. Out of 380 cases, 187 cases (49.2%) had shown abnormalities on Pap smear of which 80 cases (42%) were diagnosed as atypical glandular cells and 78 cases (41.7%) were diagnosed as adenocarcinoma. The presence of glandular abnormality on Pap smear significantly correlated with the tumor type, myometrial invasion and cervical involvement on histopathology (P < .05). Cases which had higher FIGO staging also had a higher detection rate on Pap smear (P < .05).
Conclusion:
The Pap smear may help in detection of endometrial carcinoma especially in cases with type 2 endometrial carinomas, tumor with cervical involvement and/or advanced FIGO stage.
