Related Experiment Video
Updated: Dec 9, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
A Pilot Randomized Controlled Trial Using SystemCHANGE™ Approach to Increase Physical Activity in Older Kidney
Tara O'Brien1, Cynthia L Russell2, Alai Tan1
12647The Ohio State University College of Nursing, Columbus, OH, USA.
This study shows a SystemCHANGE™ + Activity Tracker intervention is feasible for older kidney transplant recipients. It effectively increased daily steps and improved heart rate, supporting physical activity post-transplant.
Area of Science:
- Nephrology
- Cardiology
- Geriatrics
- Behavioral Science
Background:
- Cardiovascular disease (CVD) is a primary cause of mortality in kidney transplant recipients.
- Physical activity is a key modifiable factor for improving cardiovascular health after transplantation.
- Limited research exists on walking interventions for older kidney recipients to boost daily steps and health.
Purpose of the Study:
- To assess the feasibility and efficacy of the SystemCHANGE™ + Activity Tracker intervention in older kidney transplant recipients.
- To evaluate the intervention's impact on recruitment, retention, daily steps, and cardiovascular health outcomes.
- To determine if a multicomponent intervention can enhance physical activity and health in this population.
Main Methods:
- A pilot feasibility randomized clinical trial was conducted over 6 months.
- Participants received the SystemCHANGE™ (Change Habits by Applying New Goals and Experience) + Activity Tracker intervention or were in a control group.
- The intervention involved teaching participants to use system solutions and a mobile activity tracker to achieve daily step goals.
Main Results:
- The study successfully recruited and retained participants, demonstrating feasibility.
- The intervention group significantly increased daily steps compared to the control group at 3 months (P = .03).
- The intervention group experienced a significant decrease in heart rate (P = .002), while the control group showed no significant change.
Conclusions:
- The SystemCHANGE™ + Activity Tracker intervention is feasible for older kidney transplant recipients.
- This multicomponent intervention effectively increases daily steps and improves heart rate in this population.
- The findings support the use of this intervention to promote physical activity and enhance cardiovascular outcomes post-kidney transplant.
Related Concept Videos
Kidney Transplant I: Introduction
Kidney Transplant III: Nursing Management
Kidney Transplant II: Surgical Procedure
Chronic Kidney Disease I: Introduction
Bioavailability Study Design: Healthy Subjects Versus Patients
Chronic Kidney Disease III: Interprofessional Care

