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Related Concept Videos

Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

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Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
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Papillary Dermis01:11

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Muscles of the Forearm that Move the Hand and Fingers01:17

Muscles of the Forearm that Move the Hand and Fingers

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The muscles of the forearm that move the wrist, hand, and digits are numerous and diverse. They can be classified into two groups based on their location and function — the anterior and posterior compartment muscles.
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The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi...
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Spinal Nerves: Plexus I01:22

Spinal Nerves: Plexus I

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Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
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The muscles that move the forearms can be divided into four groups: forearm flexors, forearm extensors, forearm pronators, and forearm supinators. The flexors and extensors act on the elbow joint, while the pronators and supinators act on the radioulnar joints.
Forearm Flexors
The biceps brachii, brachialis, and brachioradialis are forearm flexors. The biceps brachii is made up of two heads. Its long head originates at the supraglenoid tubercle of the scapula, whereas that of the short head is...
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Reticular Dermis01:15

Reticular Dermis

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Related Experiment Video

Updated: Dec 9, 2025

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
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Elastofibroma dorsi: What's new?

Maria Serena Oliva1,2, Alessandro Smimmo1,2, Raffaele Vitiello1,2

  • 1Department of Orthopedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome.

Orthopedic Reviews
|September 11, 2020
PubMed
Summary

Elastofibroma dorsi, a rare soft tissue tumor, requires updated diagnostic approaches. This study reviews recent histological, immunohistochemical, and imaging findings to refine diagnosis.

Keywords:
Elastofibromahistologysoft tissuetumor

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Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Elastofibroma dorsi is a rare, slow-growing soft tissue tumor.
  • Typically found near the shoulder, it can occur in other locations.
  • Its pathogenesis remains largely unknown, with limited literature often restricted to case reports.

Purpose of the Study:

  • To consolidate recent advancements in elastofibroma dorsi histology.
  • To review updated immunohistochemical findings.
  • To refine the diagnostic algorithm for elastofibroma dorsi using radiological insights.

Main Methods:

  • Literature review focusing on recent histological and immunohistochemical studies.
  • Analysis of diagnostic imaging modalities for elastofibroma dorsi.
  • Synthesis of findings to propose an updated diagnostic pathway.

Main Results:

  • Recent studies highlight specific histological and immunohistochemical markers.
  • Imaging characteristics are being refined for better differentiation.
  • A comprehensive diagnostic approach integrating various findings is emerging.

Conclusions:

  • Updated histological and immunohistochemical data enhance understanding of elastofibroma dorsi.
  • Refined radiological criteria improve diagnostic accuracy.
  • An integrated diagnostic strategy is crucial for managing this rare tumor.