Related Experiment Video
Updated: Dec 9, 2025

Author Spotlight: Neuromotor Control and Recovery of Diaphragm Function Following Cervical Spinal Hemisection in Rats
Published on: June 14, 2024
[Diaphragmatic paralysis and paresis : review]
Aruran Baskaralingam1, Laurent Nicod2, Rodrigo Manzoni3
1Service de médecine interne, CHUV, 1011 Lausanne.
Diaphragmatic paresis/paralysis, affecting breathing, can be unilateral or bilateral. Treatment involves managing causes, optimizing comorbidities, and sometimes surgical or ventilatory support.
Area of Science:
- Pulmonology
- Neurology
- Thoracic Surgery
Background:
- Diaphragmatic paresis/paralysis presents with varied severity, from asymptomatic cases to respiratory failure.
- It can be unilateral or bilateral, with distinct causes and prognoses.
Purpose of the Study:
- To summarize the clinical manifestations, diagnostic findings, and management strategies for diaphragmatic dysfunction.
- To differentiate between unilateral and bilateral cases and their typical outcomes.
Main Methods:
- Review of clinical presentations and diagnostic criteria for diaphragmatic paresis/paralysis.
- Analysis of treatment options, including conservative management and surgical interventions.
Main Results:
- Respiratory functional tests show reduced respiratory pressures and a restrictive syndrome.
- Vital capacity decreases in the supine position compared to sitting.
- Unilateral paresis is often post-surgical and self-limiting; bilateral dysfunction, common in neuromuscular diseases, is typically permanent.
Conclusions:
- Effective management requires addressing underlying causes and comorbidities.
- Interventions may include diaphragmatic plication, ventilatory support, or phrenic nerve pacing for severe or permanent cases.
Related Concept Videos
Acute Respiratory Failure-III
Acute Respiratory Failure-IV
Pneumonia II: Pathophysiology
Respiratory System Abnormal Finding I: Inspection and Percussion
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
Pulmonary Embolism I: Introduction
Physical Assessment of the Respiratory Tract II: Palpation
Thoracic Palpation
Thoracic palpation detects tenderness, masses, lesions, respiratory excursions, and vocal fremitus. The nurse assesses...

