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Cholesterol embolism causing bleeding gastric ulcers.

F A Forouhar1, M Mohit, P Gardner

  • 1Pathology Department, University of Connecticut Health Center, Farmington 06032.

Annals of Clinical and Laboratory Science
|May 1, 1988
PubMed
Summary
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Atheromatous embolism can cause severe gastric bleeding and ulcers, particularly in elderly men. Surgical intervention is effective for these rare cases, highlighting the need for clinical and pathological awareness.

Area of Science:

  • Gastroenterology
  • Vascular Pathology

Background:

  • Atheromatous embolism is a rare condition where cholesterol plaques break off and travel through the bloodstream.
  • Small artery occlusions in the stomach can lead to significant gastrointestinal complications.

Observation:

  • Two cases of atheromatous embolism affecting small gastric arteries are presented.
  • Both patients experienced severe gastric bleeding and bleeding gastric ulcers identified via endoscopy.
  • These are the first reported cases linking this specific embolic event to symptomatic gastric bleeding.

Findings:

  • Gastric ulcers in these patients were secondary to arteriolar occlusions caused by atherosclerotic emboli.
  • Surgical treatment was successful in both reported cases.
  • The pathophysiology of atherosclerotic emboli and their impact on gastric vasculature was discussed.

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Implications:

  • Clinicians and pathologists should consider atheromatous embolism in elderly males presenting with upper gastrointestinal symptoms like abdominal pain.
  • Increased awareness is crucial for accurate diagnosis and timely management of this uncommon condition.
  • Understanding this phenomenon aids in differentiating it from more common causes of gastric bleeding.