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[Septicemia, portal thrombosis and congenital protein C deficiency]
J M Garnier1, M F Aillaud, P Devred
1Services de Pédiatrie et de Radiologie, CHU Nord, Marseille.
Archives Francaises De Pediatrie
|February 1, 1988
Insights
A liver abscess led to Bacteroides fragilis septicemia and portal vein thrombosis in a child with protein C deficiency. Testing for protein C is crucial in children with venous thrombosis.
Area of Science:
- Medicine
- Hematology
- Infectious Diseases
Background:
- Septicemia is a serious bloodstream infection.
- Portal vein thrombosis can lead to severe complications.
- Hereditary protein C deficiency is a risk factor for thrombosis.
Abstract:
The authors report a case of Bacteroides fragilis septicemia with left portal vein thrombosis secondary to a liver abscess discovered by ultrasonography. This thrombosis was in relation with hereditary protein C deficiency. The authors emphasize the importance of assaying for C protein along with the other physiological coagulation inhibitors in the child presenting with venous thrombosis.