Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regioselective [3 + 2] Annulation of Multisubstituted <i>N</i>-Allenamides: A Palladium-Catalyzed Heck/Tsuji-Trost Cascade Approach.

The Journal of organic chemistry·2026
Same author

Electrodeposition of UO<sub>2</sub> at Mild Temperatures in Phosphonium Ionic Liquids: A Combined Theoretical and Experimental Study.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Olfactory mucosal inflammation and barrier disruption correlate with perceived CRSwNP-associated olfactory dysfunction.

The World Allergy Organization journal·2026
Same author

The clinical value of pharmacogenomics in the pharmacotherapy of common psychiatric disorders: a macroscopic analysis based on real-world data.

BMC psychiatry·2026
Same author

Early White Matter Alterations after Mild Traumatic Brain Injury: An Exploratory Study Using Quantitative MRI and DTI.

AJNR. American journal of neuroradiology·2026
Same author

Identification and independent validation of white matter subtypes in major depressive disorder and their role in predicting treatment response.

Journal of affective disorders·2026

Related Experiment Video

Updated: Dec 9, 2025

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

15.6K

Long-term tract-specific white matter microstructural changes after acute stress.

Linghui Meng1,2, Tong Shan3, Kaiming Li4

  • 1Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Brain Imaging and Behavior
|September 12, 2020
PubMed
Summary
This summary is machine-generated.

Trauma-exposed individuals without PTSD showed white matter microstructure changes over two years, paralleling symptom improvement. These brain alterations suggest a long-term recovery process following acute stress.

Keywords:
Acute stressDTIPsychoradiologyTrauma-exposed non-PTSD

More Related Videos

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
08:27

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Published on: April 11, 2025

739
Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
10:33

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Published on: August 14, 2019

8.8K

Related Experiment Videos

Last Updated: Dec 9, 2025

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

15.6K
Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
08:27

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Published on: April 11, 2025

739
Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
10:33

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Published on: August 14, 2019

8.8K

Area of Science:

  • Neuroscience
  • Trauma Research
  • Brain Imaging

Background:

  • Acute stress significantly impacts white matter microstructure.
  • Long-term consequences and brain changes following trauma remain unclear.
  • Understanding these changes is crucial for trauma-exposed individuals.

Purpose of the Study:

  • To investigate long-term white matter microstructure changes after acute stress in trauma-exposed individuals without PTSD.
  • To explore the relationship between brain microstructure alterations and emotional distress symptom improvement.

Main Methods:

  • Diffusion tensor imaging (DTI) was used to scan 22 trauma-exposed individuals twice (25 days and 2 years post-earthquake).
  • Emotional distress was assessed using Self-Rating Anxiety/Depression Scales (SAS/SDS).
  • Automatic fiber quantification and correlation analyses were performed.

Main Results:

  • Two years post-earthquake, individuals showed altered fractional anisotropy (FA) in specific white matter tracts (superior longitudinal fasciculus, corticospinal tract).
  • Over the follow-up, increased FA in the uncinate fasciculus and corticospinal tract correlated with reduced anxiety and depression scores.
  • No direct association was found between specific brain microstructure changes and overall symptom improvement.

Conclusions:

  • White matter microstructure integrity changes in trauma-exposed individuals without PTSD parallel symptom improvement over time.
  • These brain changes represent a long-term process following acute stress.
  • External interventions may be necessary to facilitate recovery.