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Mycoplasma pneumonia and atypical acute hemorrhagic edema of infancy
Elie Saliba1, Alain Sayad2, Lama Alameddine2
1Department of Dermatology, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon.
Insights
Acute hemorrhagic edema of infancy (AHEI) is a rare vasculitis typically affecting extremities. This case highlights an unusual trunk-onset AHEI in a child with Mycoplasma pneumoniae infection.
Area of Science:
- Pediatrics
- Dermatology
- Immunology
Background:
- Acute hemorrhagic edema of infancy (AHEI) is a rare, benign leukocytoclastic vasculitis.
- Typically observed in children aged 4-24 months, it commonly affects distal extremities, face, and ears.
Observation:
- An atypical case of AHEI is presented in a 1 year 5 month old boy.
- The rash initially appeared on the trunk and back before spreading to the face and extremities.
- Mycoplasma pneumoniae IgM was positive in the patient.
Findings:
- The patient presented with an atypical, trunk-predominant rash.
- Mycoplasma pneumoniae infection was identified as a potential trigger.
- The rash resolved spontaneously within two weeks.
Implications:
- This case expands the known clinical spectrum of AHEI.
- It suggests Mycoplasma pneumoniae as a potential etiological factor in atypical AHEI presentations.
- Highlights the importance of considering infectious triggers in vasculitic syndromes.
Abstract:
Acute hemorrhagic edema of infancy is a benign rare presentation of leukocytoclastic vasculitis that affects children between 4 and 24 months of age. It usually involves the distal extremities, face, and ears. We report an atypical presentation of AHEI in a 1 year 5 months old boy starting initially over the trunk and back, then spreading to the face and extremities. Mycoplasma pneumonia IgM was found to be positive. The rash resolved spontaneously within two weeks. Herein we present a case of Mycoplasma induced AHEI with an atypical clinical presentation followed by a review of the literature.
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