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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

824
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
824
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

397
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
397

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Related Experiment Video

Updated: Dec 9, 2025

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
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Metal patch testing in patients with oral symptoms.

Misato Maeno1, Risa Tamagawa-Mineoka1, Yukiyasu Arakawa1

  • 1Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

The Journal of Dermatology
|September 13, 2020
PubMed
Summary

Patch testing for oral metal allergies shows limitations. Restoration removal efficacy is difficult to predict, even with positive patch test results, indicating further research is needed.

Keywords:
dental metalmetal allergymetal patch testingoral symptomspatch testing

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Area of Science:

  • Oral medicine
  • Allergology
  • Dermatology

Background:

  • Increasing prevalence of metal allergies necessitates understanding oral manifestations.
  • Efficacy of dental restoration removal for oral metal allergies remains debated.

Purpose of the Study:

  • To investigate the relationship between oral symptoms and metal allergies.
  • To evaluate the effectiveness of dental restoration removal in patients with oral metal allergies.

Main Methods:

  • Retrospective analysis of 60 patients presenting with oral symptoms.
  • Inclusion of patch testing data to identify metal-specific allergies.
  • Assessment of outcomes following dental restoration removal.

Main Results:

  • Abnormal oral sensation was the most frequent symptom.
  • 38% of patients showed positive allergic reactions to metals, with nickel being the most common allergen.
  • Restoration removal resulted in complete or partial remission in 3 out of 7 patients.
  • Efficacy of removal was observed in both positive (33%) and non-positive (50%) patch test groups.

Conclusions:

  • Patch testing alone is insufficient to predict the success of dental restoration removal for oral metal allergies.
  • Further investigation is required to establish reliable predictors for treatment outcomes in oral metal allergy patients.