Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Fixation and Sectioning

Fixation and Sectioning

Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens.
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...

Overview of Microscopy Techniques

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

Imaging Biological Samples with Optical Microscopy

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

Two-Dimensional Microscopy in Microbiology

Two-Dimensional Microscopy in Microbiology

Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Efficacy and safety of active surveillance and chemoablation in the management of non-muscle invasive bladder cancer (NMIBC): Systematic review and pooled analysis by the European Association of Urology-Young Academic Urologists: Urothelial Carcinoma Working Group.

Actas urologicas espanolas·2026

Same author

Real-life perception of pathology reports in urology.

Actas urologicas espanolas·2025

Same author

Biological and therapeutic implications of FGFR alterations in urothelial cancer: A systematic review from non-muscle-invasive to metastatic disease.

Actas urologicas espanolas·2025

Same author

Diagnostic accuracy of Bladder EpiCheck for upper tract urothelial carcinoma: A meta-analysis.

Actas urologicas espanolas·2025

Same author

Oncological outcomes of patients with node positive disease following neoadjuvant chemotherapy and radical cystectomy for muscle-invasive bladder cancer: A multicenter observational study of the EAU Young Academic Urologists (YAU) urothelial carcinoma working group.

Actas urologicas espanolas·2025

Same author

Epigenetic modulations and lineage plasticity in advanced prostate cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2020

Same journal

Comparative pathophysiology and pathology of transient ischemic attack, ischemic stroke, and reperfusion injury: Mechanistic and therapeutic perspectives.

Pathology, research and practice·2026

Same journal

Taraxerol targets the HIF1A-NEK6 axis to block TDE-mediated M2 macrophage polarization and inhibits NSCLC progression.

Pathology, research and practice·2026

Same journal

Tanshinone IIA promotes mitophagy by inhibiting the MARCHF5-mediated ubiquitination and degradation of FUNDC1 to alleviate spinal cord injury.

Pathology, research and practice·2026

Same journal

Rewiring lipid metabolism in diabetic kidney disease: Pathogenic networks and the therapeutic convergence of natural products.

Pathology, research and practice·2026

Same journal

Transcranial direct current stimulation improves cerebral ischemiareperfusion injury by regulating microglial ferroptosis and M1 polarization via KLF4/xCT.

Pathology, research and practice·2026

Same journal

Eicosanoids and flavonoids in asthma: Bridging inflammatory pathways and therapeutic potential.

Pathology, research and practice·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 9, 2025

Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication

Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication

Published on: December 15, 2023

Pathology without microscope: From a projection screen to a virtual slide.

R Montironi¹, A Cimadamore¹, M Scarpelli¹

¹Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.

Pathology, Research and Practice

|September 14, 2020

Summary

This summary is machine-generated.

Digital pathology has evolved significantly since the 1970s, with digitalization transforming pathology consultation and teaching. Distance learning via digital pathology is becoming a primary method, accelerated by the COVID-19 pandemic.

Keywords:

Confocal microscopy Digital pathology Glass Projection screen Slide scanner Smart working Virtual slide

More Related Videos

Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

Published on: May 20, 2016

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

Related Experiment Videos

Last Updated: Dec 9, 2025

Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication

Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication

Published on: December 15, 2023

Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

Published on: May 20, 2016

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

Area of Science:

Digital pathology
Medical informatics
Histopathology

Background:

The field of pathology has undergone significant digital transformation since the 1970s.
Digitalization is increasingly central to both pathology consultation and educational practices.
The integration of digital tools enhances accessibility and efficiency in pathology.

Discussion:

The increasing role of digitalization in pathology is a key trend.
Digital pathology facilitates remote consultations, expanding expert reach.
Technological advancements are reshaping traditional pathology workflows.

Key Insights:

Digital pathology is revolutionizing pathology services and education.
Distance teaching using digital pathology is becoming a mainstream educational modality.
The COVID-19 pandemic has accelerated the adoption of digital pathology for remote learning and collaboration.

Outlook:

Continued advancements in digital pathology are expected to further enhance diagnostic capabilities.
Digital pathology platforms will play a crucial role in the future of pathology education and practice.
The integration of artificial intelligence with digital pathology holds promise for future innovations.