[A Rare Cause of a Eosinophilic Lung Disease]

A 47-year-old male presented with dyspnoea and pulmonary nodules. He had longstanding asthma, chronic rhinosinusitis and a history of seizures, having been treated with valproic acid for years. A transbronchial biopsy and a bronchoalveolar lavage yielded a eosinophilic bronchitis and alveolitis without any malignant cells. The patient was then treated with oral corticosteroids for a few months, and the antiepileptic medication was switched to levetiracetam. Within a few months the dyspnoea improved and both the pulmonary nodules and the eosinophilia in the full blood count resolved. Eosinophilic lung diseases warrant a thorough investigation. Most likely, our patient suffers from eosinophilic granulomatosis with polyangiitis. As well, the eosinophilic lung disease might have been caused by valproic acid. Similar cases have been described in the literature.