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Influenza D virus.
Runxia Liu1, Zizhang Sheng2, Chen Huang1
1Department of Biology and Microbiology, South Dakota State University, Brookings, SD, USA.
Current Opinion in Virology
|September 15, 2020
Summary
Influenza D virus (IDV) primarily affects cattle and has spread globally. This review details IDV
Area of Science:
- Veterinary Virology
- Infectious Diseases
- Animal Health
Background:
- Influenza D virus (IDV) identified in 2011, primarily circulates in cattle.
- IDV shows frequent spillover to other species, including swine.
- Bovines are recognized as the primary reservoir for IDV.
Purpose of the Study:
- To review current knowledge on IDV epidemiology and host range.
- To discuss IDV infection biology and animal model development.
- To summarize advancements in understanding IDV pathogenesis, host response, and vaccine development.
Main Methods:
- Literature review of IDV research.
- Synthesis of epidemiological data.
- Analysis of studies on infection biology and pathogenesis.
Main Results:
- IDV is globally distributed in cattle and swine populations.
- Bovine hosts are key to IDV circulation.
- Progress has been made in understanding IDV's impact and control.
Conclusions:
- Further research is needed on IDV pathogenesis and host response.
- Development of preventive vaccines for IDV is ongoing.
- Continued surveillance is crucial for managing IDV in animal populations.
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