Diabetic autonomic neuropathy: a clinical update

Area of Science:

• Endocrinology
• Neurology
• Cardiology

Background:

• Diabetic autonomic neuropathy (DAN) is an under-recognized complication in diabetes and prediabetes.
• It affects cardiovascular, gastrointestinal, genitourinary, sudomotor, and neuroendocrine systems.
• Cardiac autonomic neuropathy is a severe complication with high mortality.

Purpose of the Study:

• To highlight the significance of diabetic autonomic neuropathy.
• To emphasize the importance of early detection and risk factor control.
• To introduce the concept of treatment-induced neuropathy (TIND) in diabetes.

Main Methods:

• Review of existing literature on diabetic autonomic neuropathy.
• Analysis of clinical manifestations across various systems.
• Identification of emerging complications like TIND.

Main Results:

• DAN presents with diverse systemic manifestations.
• Cardiac autonomic neuropathy poses a significant health risk.
• Treatment-induced neuropathy (TIND) is an emerging concern.

Conclusions:

• Early detection and management of diabetes and cardiovascular risk factors are vital.
• Preventing and treating DAN requires a comprehensive approach.
• Awareness of TIND is increasing.