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Ischemic Stroke l: Introduction

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Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

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Related Experiment Video

Updated: Jun 29, 2026

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation

Published on: March 8, 2018

Recovery of mobility function and life-space mobility after ischemic stroke: the MOBITEC-Stroke study protocol.

R Rössler^1,2, S A Bridenbaugh², S T Engelter^3,4

¹Division of Sports and Exercise Medicine, Department of Sport, Exercise, and Health, University of Basel, Birsstrasse 320 B, 4052, Basel, Switzerland.

|September 17, 2020

Summary

This study characterizes mobility recovery after stroke, identifying patient subgroups and factors influencing outdoor activity. Understanding these patterns aids in developing personalized rehabilitation strategies for improved functional outcomes.

Keywords:

Accelerometers Aging Cohort study GPS Mobility limitation Quality of life Quantitative gait analysis Spatial behaviour Walking speed

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Last Updated: Jun 29, 2026

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation

Published on: March 8, 2018

Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System

Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System

Published on: December 29, 2023

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Published on: October 11, 2024

Area of Science:

Neuroscience
Rehabilitation Medicine
Gerontology

Background:

Stroke is a leading cause of disability, with incidence rising with age.
Mobility limitations post-stroke necessitate assistance with daily activities.
Detailed understanding of mobility recovery is crucial for optimizing rehabilitation.

Purpose of the Study:

Characterize mobility, lower extremity physical function (LEPF), and life space changes in the first year post-stroke.
Identify subgroups with distinct mobility recovery trajectories.
Examine the association between LEPF changes and life-space changes.
Assess reasons for outdoor mobility, transportation use, and assistance needs.

Main Methods:

Cohort study of 59 first-stroke patients living at home.
Mobility tests (balance, strength, gait analysis) at 3, 6, 9, 12 months.
Life-space assessment with GPS and digital maps for reasons, transport, and assistance.
Statistical analysis using linear mixed effects models and growth mixture models.

Main Results:

Trajectories of mobility measures will be modeled for the overall sample and subgroups.
Exploratory analysis to identify distinct mobility recovery patterns.
Association between LEPF changes and life-space changes will be tested.
Descriptive analysis of outdoor mobility motivations, transport, and aid.

Conclusions:

Comprehensive knowledge of recovery patterns enables tailored rehabilitation.
Understanding outdoor mobility drivers allows for patient-centered goals.
Optimized rehabilitation planning can improve functional outcomes after stroke.