Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Size and Structure of Viral Genomes01:26

Size and Structure of Viral Genomes

501
Viral genomes exhibit remarkable diversity in size, structure, and composition, influencing their replication strategies and interactions with host cells. These genomes consist of either DNA or RNA and may be linear or circular. Additionally, they can be single-stranded or double-stranded, with each configuration affecting how the virus propagates within a host. RNA viruses, for instance, generally have smaller genomes than DNA viruses, a factor that contributes to their high mutation rates and...
501

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cerebrospinal fluid soluble protein tyrosine phosphatase receptor type Z detected with human natural killer-1 antibody as a practical biomarker for glioma diagnosis.

Neuro-oncology advances·2026
Same author

Biomarker-based clustering identifies distinct pulmonary function trajectories in early systemic sclerosis.

Frontiers in immunology·2026
Same author

The guide for the diagnosis and treatment of connective tissue disease-associated interstitial lung disease 2025.

Respiratory investigation·2026
Same author

Evolution-guided prioritization identifies a tissue-specific phosphorylation switch on herpes simplex virus 1 UL7 regulating viral replication and pathogenicity.

Journal of virology·2026
Same authorSame journal

[Elucidation of an Intrinsic Immune Evasion Mechanism in Herpes Encephalitis].

Uirusu·2026
Same author

Author Correction: GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region.

Nature communications·2026

Related Experiment Video

Updated: Dec 8, 2025

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
12:22

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

Published on: April 2, 2012

17.8K

[Recent Advances in Basic Research on the Herpes Simplex Virus].

Yasushi Kawaguchi1

  • 1Division of Molecular Virology, Department of Microbiology and Immunology,The Institute of Medical Science,The University of Tokyo.

Uirusu
|September 17, 2020
PubMed
Summary
This summary is machine-generated.

Herpes simplex virus (HSV) causes significant diseases, including lethal encephalitis. New research offers hope for novel therapies and prevention strategies against HSV infections and their link to HIV.

More Related Videos

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
11:56

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

11.5K
Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
08:31

Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals

Published on: September 20, 2021

3.6K

Related Experiment Videos

Last Updated: Dec 8, 2025

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
12:22

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

Published on: April 2, 2012

17.8K
Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
11:56

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

11.5K
Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
08:31

Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals

Published on: September 20, 2021

3.6K

Area of Science:

  • Virology
  • Infectious Diseases
  • Neuroscience

Context:

  • Herpes simplex virus (HSV) is a prevalent human pathogen responsible for mucocutaneous diseases and severe neurological conditions like herpes simplex encephalitis.
  • Despite existing antiviral drugs, significant unmet medical needs persist for managing HSV infections.
  • Genital herpes increases the risk of HIV acquisition and transmission by 2-4 fold.

Purpose:

  • To review recent advances in basic HSV research.
  • To highlight the implications of recent findings for developing new therapeutic and prophylactic agents against HSV infections.

Summary:

  • This review focuses on recent basic research in HSV, emphasizing novel findings.
  • The research explores potential therapeutic and prophylactic strategies to combat HSV infections.
  • Understanding HSV pathogenesis is crucial for addressing its associated health risks, including increased HIV susceptibility.

Impact:

  • Advances in understanding HSV biology can lead to improved treatments for herpes labialis, genital herpes, and herpes simplex encephalitis.
  • Development of novel agents is critical to address the limitations of current antiviral therapies.
  • Targeting HSV may also mitigate the increased risk of HIV infection and transmission associated with genital herpes.