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Updated: Dec 8, 2025

Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Macromolecular biomarkers of chronic obstructive pulmonary disease in exhaled breath condensate
Somayeh Kazeminasab1,2, Babak Emamalizadeh3, Abolghasem Jouyban1,4
1Pharmaceutical Analysis Research Center & Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51656-65811, Iran.
Abstract:
Biomarkers provide important diagnostic and prognostic information on heterogeneous diseases such as chronic obstructive pulmonary disease (COPD). However, finding a suitable specimen for clinical analysis of biomarkers for COPD is challenging. Exhaled breath condensate (EBC) sampling is noninvasive, rapid, cost-effective and easily repeatable. EBC sampling has also provided recent progress in the identification of biological macromolecules, such as lipids, proteins and DNA in EBC samples, which has increased its utility for clinical scientists. In this article, we review applications involving EBC sampling for the analysis of COPD biomarkers and discuss its future potential.
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