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Related Concept Videos

Teeth01:15

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
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Tooth Anatomy01:21

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The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
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The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
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Updated: Dec 8, 2025

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
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Tooth Loss and Dementia: A Critical Examination.

W M Thomson1, Y Barak2

  • 1Department of Oral Sciences, Sir John Walsh Research Institute, School of Dentistry, The University of Otago, Dunedin, New Zealand.

Journal of Dental Research
|September 18, 2020
PubMed
Summary
This summary is machine-generated.

Childhood cognitive function influences lifelong oral health, impacting tooth loss and cognitive decline in older adults. Better early cognition correlates with better oral health and preserved cognitive function later in life.

Keywords:
cognitive declineepidemiologygerontologynarrative reviewolder peoplerisk factors

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Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • Dementia significantly contributes to disability in aging populations.
  • While tooth loss is linked to dementia, existing evidence and proposed mechanisms are inconclusive.
  • Risk factors for dementia include low education, hypertension, hearing loss, and lifestyle choices.

Purpose of the Study:

  • To propose a life course explanation for the association between tooth loss and cognitive decline in older adults.
  • To investigate the role of early-life cognitive function in the relationship between oral health and cognitive aging.

Main Methods:

  • Utilized a life course approach analyzing data from longstanding cohort studies.
  • Examined the correlation between childhood cognitive function, lifelong oral health, and cognitive function in older age.

Main Results:

  • Individuals with higher childhood cognitive function exhibit better oral health and less tooth loss throughout life.
  • Poorer childhood cognitive function is associated with higher disease rates, reduced dental care access, and increased tooth loss.
  • Cognitive differences observed from mid-adulthood are most pronounced in old age, with greater tooth loss in those with lower early cognitive ability.

Conclusions:

  • The association between tooth loss and cognitive decline in older adults is primarily explained by cognitive function established in childhood.
  • Early-life cognitive ability influences both oral health maintenance and cognitive aging trajectories.
  • This life course perspective offers an empirically supported explanation for the observed link between missing teeth and cognitive impairment.