Effect of the electrode array-retina gap distance on visual function in patients with the Argus II retinal prosthesis
Abhishek Naidu1, Nimra Ghani2, Mohammad Saad Yazdanie2
1Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, 11794, USA. Abhishek.naidu@stonybrookmedicine.edu.
BMC Ophthalmology
|September 18, 2020
Summary
The Argus II Retinal Prosthesis electrode array-retina gap distance impacts Square Localization visual function in some patients. Optimal visual outcomes may not require complete array-retina apposition.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Retinal Prosthetics
Background:
- Visual outcomes after Argus II Retinal Prosthesis implantation depend on electrode array positioning.
- Understanding the relationship between array-retina gap and visual function is crucial.
Purpose of the Study:
- To investigate the correlation between electrode array-retina gap distance and visual function outcomes.
- To assess the impact on sensitivity detection thresholds in Argus II patients.
Main Methods:
- Retrospective analysis of five Argus II Retinal Prosthesis patients.
- Measurement of electrode array-retina gap using Cirrus HD-OCT.
- Evaluation of visual function tests (Square Localization, Direction of Motion) with device ON and OFF.
Main Results:
- Electrode array-retina gap distance affected Square Localization (SL) performance in a patient-dependent manner.
- Three patients showed improved SL visual function with the device ON.
- No significant effect of gap distance on Direction of Motion (DOM) or sensitivity thresholds was observed.
Conclusions:
- Electrode array-retina gap distance may influence SL visual function outcomes in Argus II patients.
- The effect of gap distance is patient-specific and may not necessitate complete array-retina apposition for optimal results.
