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PARP-1 Flips the Epigenetic Switch on Obesity

Carla E Margulies1, Andreas G Ladurner2

  • 1Biomedical Center, Department of Molecular Biology, Ludwig-Maximilians-University Munich, Grosshaderner Strasse 9, 82152 Planegg, Germany.

Molecular Cell
|September 18, 2020
PubMed
Summary

Poly (ADP-ribose) polymerases (PARP) enzymes regulate adipogenesis. PARP-1 modifies histone H2B, impacting gene expression and fat cell development.

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