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Published on: September 20, 2024
Tomographically normal partner eye in very asymmetrical corneal ectasia: biomechanical analysis
Doris Fraenkel1, Loïc Hamon, Loay Daas
1From the Department of Ophthalmology, Saarland University Medical Center UKS (Fraenkel, Hamon, Daas, Flockerzi, Suffo, Seitz), and Institute of Experimental Ophthalmology, Saarland University (Eppig), Homburg/Saar, and AMIPLANT GmbH (Eppig), Schnaittach, Germany.
Purpose:
To point out the biomechanical changes of the topographically and tomographically normal partner eye (NPE) in patients with very asymmetrical corneal ectasia.
Setting:
Department of Ophthalmology, Saarland University Medical Center in Homburg/Saar, Germany.
Design:
Retrospective study.
Methods:
The topographical and tomographical results of the NPE were assessed using the Pentacam HR and the biomechanical corneal properties using the Ocular Response Analyzer (keratoconus match index [KMI], corneal hysteresis [CH], and corneal resistance factor [CRF]) and the Corvis ST (topographic biomechanical index [TBI] and Corvis biomechanical index) and compared those results with a normal control group (CG).
Results:
The clinical records of 26 patients recruited from the Homburg Keratoconus Center diagnosed with a very asymmetrical corneal ectasia were reviewed. The NPE (8.5 ± 1.5 mm Hg) showed a significantly more pathological CH (P < .001) compared with the CG. The CRF was also significantly more pathological (P = .04) for the NPE (8.3 ± 1.5 mm Hg) compared with the CG. The NPE (0.62 ± 0.32) showed a nonsignificant (P = .08) more pathological KMI compared with the CG. Nineteen (73.1%) of 26 NPE had a KMI less than 0.72 and were considered pathological. Compared with the CG, the TBI of the NPE (0.19 ± 0.25) did not differ significantly overall (P = .57). However, 5 (19.2%) of 26 eyes had a TBI more than 0.29 and were considered pathological.
Conclusions:
Topographically and tomographically NPEs in very asymmetrical corneal ectasia frequently showed biomechanical changes. This should be considered before planning any type of refractive corneal surgery in such patients.

