Related Experiment Video

Updated: Dec 8, 2025

Propagation of Dental and Respiratory Cells and Organs in Microgravity
06:29

Propagation of Dental and Respiratory Cells and Organs in Microgravity

Published on: May 25, 2021

2.3K

Osteoclasts and Microgravity

John Kelly Smith1

  • 1Departments of Academic Affairs and Biomedical Sciences, James H Quillen College of Medicine, East Tennessee State University, P.O. Box 70300, Johnson City, TN 37614, USA.

Life (Basel, Switzerland)
|September 19, 2020
PubMed

Keywords:
M-CSFRANKLbonecytokinesmicrogravityosteoblastsosteoclastsosteocytesspaceflight

More Related Videos

Culturing Lymphocytes in Simulated Microgravity Using a Rotary Cell Culture System09:28

Culturing Lymphocytes in Simulated Microgravity Using a Rotary Cell Culture System

Published on: August 25, 2022

3.3K
In Vitro Growth of Mouse Preantral Follicles Under Simulated Microgravity10:48

In Vitro Growth of Mouse Preantral Follicles Under Simulated Microgravity

Published on: December 17, 2017

8.7K

Related Concept Videos

Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.6K
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
Acceleration due to Gravity on Other Planets01:24

Acceleration due to Gravity on Other Planets

The gravitational acceleration of an object near the Earth's surface is called the acceleration due to gravity. It can be measured by conducting simple experiments on Earth. However, such an experiment is impossible to conduct on the surface of other planets.
Astronomical observations are thus used to measure the acceleration due to gravity on other planets. This can be determined by observing the effect of a planet's gravity on objects close to it. The crucial factor that helps in this...
4.7K
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
39.8K
Cell-matrix's Response to Mechanical Forces01:13

Cell-matrix's Response to Mechanical Forces

In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...
3.2K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.5K