Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Revitalization in Traumatized Immature Teeth With External Inflammatory Root Resorption: A Systematic Review.

Dental traumatology : official publication of International Association for Dental Traumatology·2026
Same author

Lipoteichoic acid induces IL-6 production in human pulp stromal cells through TLR2-mediated NF-κB nuclear translocation.

Archives of oral biology·2026
Same author

Bioactive Materials and Novel Techniques in Endodontics: Translational Advances for Clinical Practice.

Journal of functional biomaterials·2026
Same author

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA-Seq Analysis.

International endodontic journal·2026
Same author

Cytotoxicity testing of dental materials: Establishment of a 3D-printed dentin barrier culture system.

Dental materials : official publication of the Academy of Dental Materials·2025
Same author

In-vitro-cytotoxicity of cariostatic agents based on fluorides and lanthanide salts in L-929 fibroblasts.

Clinical oral investigations·2025

Related Experiment Video

Updated: Dec 8, 2025

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
02:33

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

2.4K

Cell-Free Approaches for Dental Pulp Tissue Engineering.

Kerstin M Galler1, Matthias Widbiller1

  • 1Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.

Journal of Endodontics
|September 20, 2020
PubMed
Summary

Cell transplantation shows promise for dental pulp regeneration, but cell homing offers a potentially more cost-effective alternative by recruiting resident stem cells using dentin-derived growth factors.

Keywords:
Cell homingdental pulpdental pulp stem cellsdentin matrix proteinsscaffoldtissue engineering

More Related Videos

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods
14:52

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

27.1K
Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
03:45

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

3.0K

Related Experiment Videos

Last Updated: Dec 8, 2025

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
02:33

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

2.4K
Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods
14:52

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

27.1K
Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
03:45

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

3.0K

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Stem Cell Biology

Background:

  • Cell transplantation and cell homing are strategies for dental pulp tissue engineering.
  • Cell transplantation has demonstrated potential for regenerating a functional dentin-pulp complex, with recent clinical evaluations.
  • High costs and efforts associated with cell transplantation necessitate exploring alternative approaches like cell homing.

Purpose of the Study:

  • To discuss the latest developments in cell homing for dental pulp tissue engineering.
  • To explore the recruitment of resident stem cells using dentin-derived growth factors.
  • To evaluate injectable fibrin-based scaffolds for cell homing applications.

Main Methods:

  • Review of recent advancements in cell homing strategies.
  • Analysis of dentin-derived growth factors for stem cell recruitment.
  • Investigation of injectable fibrin-based scaffolds as delivery vehicles.

Main Results:

  • Cell homing presents a viable alternative to cell transplantation for dental pulp regeneration.
  • Dentin-derived growth factors can effectively recruit resident stem cells.
  • Injectable fibrin scaffolds show potential for facilitating cell homing.

Conclusions:

  • Cell homing, utilizing dentin-derived growth factors and fibrin scaffolds, is a promising and potentially cost-effective approach for dental pulp tissue engineering.
  • Further research into cell homing mechanisms and scaffold optimization is warranted.
  • This strategy may overcome the limitations of current cell transplantation methods.