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Updated: Dec 8, 2025

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
Published on: January 16, 2016
Experimental insight into enzyme catalysis and dynamics: A review on applications of state of art spectroscopic
Puspal Mukherjee1, Prashant Chandra Singh1
1School of Chemical Sciences, Indian Association for the Cultivation of Science, Kolkata, West Bengal, India.
Abstract:
Enzymes are dynamic in nature and understanding their activity depends on exploring their overall structural fluctuation as well as transformation at the active site in free state as well as turnover conditions. In this chapter, the application of several different spectroscopy techniques viz. single molecule spectroscopy, ultrafast spectroscopy and Raman spectroscopy in the context of enzyme dynamics and catalysis are discussed. The importance of such studies are significant in the understanding of new discoveries of drugs, cure for some lethal diseases, gene modification as well as in industrial applications.
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