Related Experiment Video
Updated: Dec 8, 2025

A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer
Published on: December 26, 2016
Multiorgan metastatic invasive lobular Carcinoma initially presenting as diplopia
Amanda Allen1, Nishi Mehta1, Ismail Elbaz Younes2
1University of Illinois at Chicago, Department of Radiology, 1740 W Taylor St, Chicago, IL 60612, USA.
A rare case of invasive lobular carcinoma metastasized to the orbits and kidney presented in a 76-year-old woman. This subtype of breast cancer shows unusual metastatic patterns, often affecting the orbits and kidneys.
Area of Science:
- Oncology
- Pathology
Background:
- Invasive lobular carcinoma (ILC) is a less common breast cancer subtype.
- ILC presents unique diagnostic challenges due to its subtle imaging characteristics compared to invasive ductal carcinoma.
Observation:
- A 76-year-old woman presented with diplopia, leading to the diagnosis of multiorgan metastatic ILC.
- Biopsies confirmed metastatic ILC involving the orbits and kidney.
Findings:
- ILC exhibits an unusual metastatic pattern, frequently involving the orbits, ovaries, gastrointestinal tract, retroperitoneum, and bone.
- Metastasis to these sites can be the initial presentation of ILC.
Implications:
- Increased awareness of ILC's metastatic patterns is crucial for early diagnosis.
- Imaging findings in specific organs should prompt consideration of ILC metastasis, especially in at-risk populations.
More Related Videos
08:15A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth
Published on: February 2, 2024
06:15Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024