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Updated: Dec 8, 2025
08:31
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
4.2K
Initial experience of a MitraClip valve repair program in Spain
Daniel Henández-Vaquero1,2,3, Isaac Pascual1,2,3, Marcel Almendarez1,2
1Heart Area, Hospital Universitario Central de Asturias, Oviedo, Spain.
Annals of Translational Medicine
|September 21, 2020
Summary
Transcatheter mitral valve repair (TMVR) is a safe procedure for symptomatic mitral regurgitation (MR), showing reduced mortality and heart failure hospitalizations within one year. Outcomes are sustained, with improved functional class.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Devices
Background:
- Symptomatic mitral regurgitation (MR) poses significant clinical challenges.
- Transcatheter mitral valve repair (TMVR) offers a minimally invasive treatment option.
- Understanding outcomes based on MR etiology is crucial for patient selection.
Purpose of the Study:
- To evaluate the one-year clinical outcomes of transcatheter mitral valve repair (TMVR).
- To analyze outcomes stratified by the etiology of symptomatic mitral regurgitation (MR).
- To assess the safety and efficacy of TMVR in a real-world patient cohort.
Main Methods:
- Prospective data collection from a single high-volume center.
- Inclusion of consecutive patients undergoing TMVR for symptomatic MR.
- One-year follow-up to assess clinical endpoints.
Main Results:
- 81 patients underwent TMVR; 59% had functional MR (FMR).
- Procedural success was high (88.9%); 23.5% experienced primary combined endpoint events.
- One-year mortality was 20%, and HF hospitalization was 23.5%; previous revascularization and redo TMVR predicted adverse events.
Conclusions:
- TMVR using the Mitraclip device is safe with high procedural success.
- One-year outcomes demonstrate reduced all-cause death and heart failure admissions.
- Sustained MR reduction and improved functional class were observed post-TMVR.
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