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Fractionation mapping software to map ganglionated plexus sites during sinus rhythm
Tolga Aksu1, Kivanc Yalin2, Rakesh Gopinathannair3
1Department of Cardiology, Kocaeli Derince Training and Research Hospital, University of Health Science, Kocaeli, Turkey.
Journal of Cardiovascular Electrophysiology
|September 21, 2020
Summary
Ablation of ganglionated plexuses (GPs) offers a new treatment for vasovagal syncope. This study tested software to reliably detect GP locations during electrophysiologic studies, improving treatment accuracy.
Area of Science:
- Cardiology
- Electrophysiology
- Neuroscience
Background:
- Ganglionated plexuses (GPs) ablation is an emerging therapy for refractory vasovagal syncope.
- Accurate localization of GPs is crucial for successful ablation due to anatomical variations.
Observation:
- This case study evaluated the Ensite system's fractionation mapping software for GP detection.
- The software's ability to detect GP localization was compared against a validated fractionated electrogram-based strategy.
Findings:
- Fractionation mapping software demonstrated potential for reproducible GP detection during electrophysiologic study.
- The software's performance was assessed in relation to previously established methods for identifying fractionated electrograms.
Implications:
- This technique could enhance the precision and success rates of ganglionated plexus ablation for vasovagal syncope.
- Standardized GP detection methods are essential for advancing this minimally invasive treatment.
- Further research is warranted to validate this software in larger patient cohorts.
