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Related Experiment Video

Updated: Dec 8, 2025

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SEEP-CI: A Structured Economic Evaluation Process for Complex Health System Interventions.

Jason Madan1, Meghan Bruce Kumar2,3, Miriam Taegtmeyer2

  • 1Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.

International Journal of Environmental Research and Public Health
|September 22, 2020
PubMed
Summary

Economic evaluation of complex health interventions is difficult. The Structured Economic Evaluation Process for Complex Health System Interventions (SEEP-CI) offers a new framework to assess intervention impact and justify investment.

Keywords:
complex interventioneconomic evaluationhealth system interventions

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Area of Science:

  • Health economics
  • Health services research
  • Public health

Background:

  • Economic evaluation of complex health system interventions presents significant methodological challenges.
  • Existing guidance for addressing these challenges in complex interventions is limited.
  • The REACHOUT consortium faced these challenges during community health program evaluations in Africa and Asia.

Purpose of the Study:

  • To develop a structured process for economic evaluation of complex health system interventions.
  • To create a framework (SEEP-CI) to assess the likelihood of achieving impact and justify investment in complex interventions.
  • To illustrate the application of SEEP-CI using the REACHOUT project.

Main Methods:

  • Development of the Structured Economic Evaluation Process for Complex Health System Interventions (SEEP-CI).
  • Application of SEEP-CI to retrospective analysis of the REACHOUT project.
  • Identification of potential impact, causal mechanisms, and data collection guidance.

Main Results:

  • SEEP-CI can identify relevant outcomes and causal pathways for complex interventions.
  • The process aids in defining the required health gain to justify investment.
  • SEEP-CI helps clarify necessary assumptions for credible health gain estimations.

Conclusions:

  • The SEEP-CI provides a structured approach to address economic evaluation challenges in complex health system interventions.
  • Further research is needed to validate the feasibility and acceptability of SEEP-CI across different contexts.
  • SEEP-CI can guide decision-making regarding investment in complex health programs.