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Related Experiment Videos

Remote Multicomponent Rehabilitation in Intensive Care Unit Survivors: A Randomized Clinical Trial.

Brenda O'Neill1, Judy M Bradley2, Bronwen Connolly2,3

  • 1Institute of Nursing and Health Research, School of Health Sciences, Ulster University, Belfast, Northern Ireland.

JAMA
|May 18, 2026
PubMed
Summary

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A 6-week remote rehabilitation program did not improve quality of life for critical care survivors. While it enhanced physical function and reduced fatigue and anxiety, it did not significantly impact overall health-related quality of life.

Area of Science:

  • Critical care medicine
  • Rehabilitation science
  • Health services research

Background:

  • Evidence for remote rehabilitation in critical care survivors is limited.
  • Survivors of critical illness often experience long-term physical and psychological impairments.
  • Intensive care unit (ICU) survivors require effective post-discharge support.

Purpose of the Study:

  • To evaluate a 6-week remote, multicomponent rehabilitation intervention for ICU survivors.
  • To compare the intervention's effect on health-related quality of life against standard care.
  • To assess secondary outcomes including physical function, fatigue, anxiety, and depression.

Main Methods:

  • A pragmatic, multicenter, randomized clinical trial involving 429 adult ICU survivors.

Related Experiment Videos

  • Participants received either a 6-week remote rehabilitation program or standard care.
  • Health-related quality of life was measured using the EQ-5D-5L at 8 weeks post-discharge.

    • Main Results:

    • The intervention group showed a mean EQ-5D-5L score of 0.69 vs. 0.67 in the standard care group (adjusted difference: 0.04, P=0.05).
    • Leg strength, exercise capacity, fatigue, and anxiety improved with the intervention.
    • No significant changes were observed in depression or illness perception.

    Conclusions:

    • A 6-week multicomponent rehabilitation program did not significantly improve health-related quality of life in ICU survivors.
    • The intervention demonstrated benefits in specific secondary outcomes like physical function and psychological well-being.
    • Further research may explore longer or adapted rehabilitation strategies for this population.