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Updated: Dec 8, 2025

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An Improved Method for the Preparation of Type I Collagen From Skin
Published on: January 21, 2014
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Sea Cucumber Derived Type I Collagen: A Comprehensive Review
Tharindu R L Senadheera1, Deepika Dave1,2, Fereidoon Shahidi1
1Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1B 3X9, Canada.
Marine Drugs
|September 23, 2020
Summary
Marine invertebrates, like sea cucumbers, offer a promising alternative source for type I collagen. This review explores their potential, extraction methods, and properties for food and non-food applications.
Area of Science:
- Biochemistry
- Marine Biology
- Biotechnology
Background:
- Collagen, a major fibrillar protein, is abundant in marine invertebrate tissues, particularly type I collagen.
- Mammalian collagen use is restricted due to health risks and religious constraints, necessitating alternative sources.
- Marine invertebrates and their by-products are underutilized sources of collagen.
Purpose of the Study:
- To identify sea cucumber as a potential source of collagen.
- To review collagen extraction, isolation, and characterization from marine invertebrates.
- To discuss the opportunities and challenges of utilizing marine-derived collagen.
Main Methods:
- Literature review focusing on marine invertebrate collagen.
- Analysis of collagen extraction and isolation techniques.
- Evaluation of physicochemical properties and characterization methods.
Main Results:
- Sea cucumber is identified as a viable source for type I collagen.
- Various methods for collagen extraction and isolation from marine invertebrates are discussed.
- Physicochemical properties of marine-derived collagen are detailed.
Conclusions:
- Marine invertebrates represent a significant, underexplored source for collagen production.
- Further research into extraction and characterization can unlock the potential of marine collagen.
- Sea cucumber collagen offers promising applications in food and non-food industries.
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