Related Experiment Video

Updated: Dec 8, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

3.8K

Improvement in Hypertension Management with Pharmacological and Non- Pharmacological Approaches: Current Perspectives

Dongsheng Hong1, Wenya Shan1

  • 1Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Current Pharmaceutical Design
|September 23, 2020
PubMed

Insights

Effective hypertension management requires personalized strategies, combining pharmacological and non-pharmacological approaches. This review explores optimal blood pressure targets and treatment interventions for better cardiovascular disease prevention.

Area of Science:

  • Cardiology
  • Public Health
  • Pharmacology

Background:

  • Hypertension management remains a significant global public health challenge.
  • Optimal blood pressure targets lack universal consensus in current guidelines.
  • Individualized patient characteristics necessitate tailored hypertension management strategies.

Purpose of the Study:

  • To review and synthesize current literature on pharmacological and non-pharmacological approaches to hypertension management.
  • To establish practical recommendations for optimizing blood pressure control.
  • To address the urgent need for effective, individualized hypertension treatment.

Main Methods:

  • Systematic review of PubMed-published reports on hypertension management.
  • Independent and collective review of pharmacological and non-pharmacological interventions.
  • Panel establishment of practical hypertension management recommendations.

Main Results:

  • Pharmacological agents vary in mechanisms, characteristics, and adverse reactions, often requiring combination therapy.
  • Non-pharmacological treatments enhance adherence and long-term blood pressure control, reducing cardiovascular risks.
  • Individualized treatment is crucial for achieving target blood pressure ranges and disease progression slowing.

Conclusions:

  • This review synthesizes literature on guideline principles, pharmacological treatments, biotechnology, surgical interventions, and big data/AI applications in hypertension.
  • Behavioral interventions and technical means are highlighted for managing hypertension.
  • Future directions are provided to facilitate the clinical implementation of current and developing knowledge in hypertension care.
Abstract

Keywords:
Antihypertensive drugsartificial intelligencebiotechnology interferencecardiovascular diseaseshypertension managementpharmacological approaches

More Related Videos

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

1.0K
Multidisciplinary Approach to Obesity Management: A Case Report05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

736

Related Concept Videos

Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
404
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
222
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.5K
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
538
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
124
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
311